The Biochemistry of Retinoid Signaling II The Physiology of Vitamin A – Uptake Transport Metabolism and Signaling (Subcellular Biochemistry)

The role of vitamin A in living organisms has been known throughout human history. In the last 100 years the biochemical nature of vitamin A and its active derivative retinoic acid its physiological impact on growth processes and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions encompassing embryogenesis postnatal development to old age. A wealth of intercellular interactions intracellular signaling systems and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life.  This book series with chapters authored by experts in every aspect of this complex field unifies the knowledge base and mechanisms currently known in detailed engaging well illustrated focused chapters that synthesize information for each specific area.

In view of the recent information explosion in this field it is timely to publish a contemporary comprehensive book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action its role in physiology development and continued well being and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases.